Specialized spaces must be maintained at a positive or negative pressure to ensure safety and compliance to standards. Ventilation systems that maintain and control room pressurization within hospital isolation rooms are typically classified as either Airborne Infection Isolation – AII Rooms (Negative to hallway) or Protective Environment – PE room (Positive to hallway). These rooms are designed to comply with various standards such as ASHRAE 170-2008, FGI/AIA 2010, and CDC. To comply with the standards, these rooms typically are set up to maintain a small pressure differential relative to a hallway or anteroom. This pressure is stipulated in the standards as a minimum of 0.01 in. H2O (2.5 Pa).
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